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Nonlinear neuroelectrothermodynamics of a cell |
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II. Nonlinear Cell Neuroelectrothermodynamics. Neurofrequency Model of Rational Mind. Epiphysis Microcrystals as Current Sources. |
The chapter Nonlinear Cell Neuroelectrothermodynamics. Neurofrequency Model of Rational Mind. Epiphysis Microcrystals as Current Sources, including subsections Thermal-Electric Homeostasis, Thermal-Electric Mechanisms and Models of Neuron Stimulation Transformation, Acervulus Crystals as Controlled Current Sources, on the whole is the live cellular neuroglial structures neurobioelectronics foundation, constructed on the basis of the thermal-electric theory of stimulants transformation neurogeneration in connection with the environment.
Neurobioelectronics scientific foundation is presented as theoretical and experimental nonlinear cell neuroelectrothermodynamics, whose construction was performed with original preconditions, considerably differing from key concepts, theories, techniques of measurements and estimations of neurophysiology and neurobiology.
Among new concepts and original preconditions the following ones are the main:
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The presentation of the excitable membrane as an insulator, i.e. a dielectric in plane capacitor, is not adequate. In fact, the excitable neuromembrane of a single unit is characterised by complex temperature dependence of conduction, on which there are areas of conduction both with positive and negative temperature coefficient of conduction in 10-45° С temperature range.
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It is a procedural mistake of measuring to spread the patch-clamp technique in neurophysiology as a universal technique not taking into account the electric nonlinear properties of membranes at various temperatures. It would be properly to use the patch-clamp technique in the cases when membrane conduction reduces at temperature rising. If membrane conduction increases at temperature rising, the current latching approach should be used. Otherwise, at the defined value of current and voltage there arise membrane conductivity jumps, distorting the real picture of phenomena.
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It is not proper to apply Hodzhkin-Huxley's theory and model to the description of the neuroglial complex in whole. In respect to a particular case of the axonal membrane the model is also incomplete as it does not take into account nonlinear thermal-electric processes of the membrane, nonlinear equivalent bioinductance, does not show that for neurostructures functioning the nerve impulses repetition center frequency is biologically significant, etc.
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The neurobiology representation of nerve impulses amplitude remaining constant at neurostructures functioning requires correction. In fact, nerve impulses can be linearly totalized and subtracted. At specified electric nonlinear membrane parameters and weak programmed external influences nerve impulses amplitudes may increase many times.
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It does not arise from the classical concepts of neurobiology that the nerve cell may generate high-power squared non-nerve pulses and that the human brain contains solid-state quasi-ideal constant microcurrent sources, having paradoxical nonlinear characteristics, which appear at currents of 10-11 — 10-12 A, which does not comply with physical electronics concepts.
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It does not proceed from neurobiology that electric nonlinear biostructures may become excited and tune to congenital nonlinear resonance biofrequencies by weak external electrophysical actions, by contact and noncontact methods, from short and long distances. Properly, such actions are basic ones of the new scientific field named "Neurofrequency Ecology".
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